PrP charge structure encodes interdomain interactions
نویسندگان
چکیده
منابع مشابه
PrP charge structure encodes interdomain interactions.
Almost all proteins contain charged residues, and their chain distribution is tailored to fulfill essential ionic interactions for folding, binding and catalysis. Among proteins, the hinged two-domain chain of the cellular prion protein (PrP(C)) exhibits a peculiar charge structure with unclear consequences in its structural malleability. To decipher the charge design role, we generated charge-...
متن کاملInterdomain Interactions Support Interdomain Communication in Human Pin1
Pin1 is an essential mitotic regulator consisting of a peptidyl-prolyl isomerase (PPIase) domain flexibly tethered to a smaller Trp-Trp (WW) binding domain. Communication between these domains is important for Pin1 in vivo activity; however, the atomic basis for this communication has remained elusive. Our previous nuclear magnetic resonance (NMR) studies of Pin1 functional dynamics suggested t...
متن کاملStructure Encodes Exactly Jordan Structure
We prove that for all 1 ≤ p ≤ ∞, p 6= 2, the L spaces associated to two von Neumann algebras M, N are isometrically isomorphic if and only if M and N are Jordan *-isomorphic. This follows from a noncommutative L Banach-Stone theorem: a specific decomposition for surjective isometries of noncommutative L spaces.
متن کاملCharge Resonance and Charge Transfer Interactions
Abstrtct Chrge resonance interaction in naphthalene homomd heterodimer cations is studied by photodissociation spc'troscopy ofthe charge resonance and the local excitation transitions. The resonance interaction in naphthalene dimer cation is slightly weaker than that ofa benzene dimer cation because ofpartial overlapping ofthe respective aromatic rings. A local excitationband ofthe benzene cati...
متن کاملNoncommutative L Structure Encodes Exactly Jordan Structure
We prove that for all 1 ≤ p ≤ ∞, p 6= 2, the Lp spaces associated to two von Neumann algebrasM, N are isometrically isomorphic if and only if M and N are Jordan *-isomorphic. This follows from a noncommutative Lp Banach-Stone theorem: a specific decomposition for surjective isometries of noncommutative Lp spaces.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Scientific Reports
سال: 2015
ISSN: 2045-2322
DOI: 10.1038/srep13623